SkinnyRx vs Yucca Health

All-in cost at every dose, fee structure, care model, pharmacy disclosure and terms — compared on one basis.

Direct answer

Over a first year at a 10 mg maintenance dose, Yucca Health costs about $3,096 against $3,588 — a difference of $492, or roughly 14% of the larger figure.

Both hold one price at every strength, so the ranking does not change with your dose.

For context: across 32 tracked tirzepatide telehealth programmes, 17 publish a price we could capture, and the cheapest verified all-in cost is $215 a month at a 10 mg maintenance dose — about $2,580 for a first year. Compounded preparations are not FDA-approved. Prices captured 2026-08-05.

Price basis

All-in monthly cost = medication + any recurring fee, at a named dose, before tax and before prepaid discounts. Captured 2026-08-05. How we verify a price.

SkinnyRx vs Yucca Health at every dose

A single headline figure assumes a maintenance dose neither you nor your prescriber has chosen yet. This is the same comparison at all six strengths.

SkinnyRx against Yucca Health at every dose

$251$265$278$292$3062.5 mg5 mg7.5 mg10 mg12.5 mg15 mgSkinnyRxYucca Health
All-in monthly cost, membership included. Where the lines cross, the cheaper programme changes with your dose.
All-in monthly cost by dose tier, membership included. Captured 2026-08-05.
DoseSkinnyRxYucca HealthCheaper
2.5 mg$299$258Yucca Health
5 mg$299$258Yucca Health
7.5 mg$299$258Yucca Health
10 mg$299$258Yucca Health
12.5 mg$299$258Yucca Health
15 mg$299$258Yucca Health

What differs beyond price

Price is the easiest thing to compare and rarely the thing that decides satisfaction. These are the attributes each programme publishes.

Published attributes for both programmes. “Not published” means we could not find it stated, not that it does not exist.
AttributeSkinnyRxYucca Health
Pricing modelflat at every doseflat at every dose
Membershipnonenone
Prepaid ratenone published$225
Visit modelasyncasync
Labsnot requirednot required
Pharmacy disclosurenot namednamed physicians
Cancellationno membership on compounded6-month term
Regulatory statuscompounded, not FDA-approvedcompounded, not FDA-approved
Evidence status✓ verified at source✓ verified at source

Which one, for whom

If you want the lowest total cost: Yucca Health at about $3,096 for a first year.

If you want budget certainty: neither has an advantage — both use the same pricing model.

If you want to verify the supply chain: Yucca Health, which names its dispensing pharmacy.

If you may need to stop early: compare the cancellation rows above before prepaying. Compounded medication is generally not refundable once it has shipped, so a multi-month term is the wrong structure during titration, when intolerance is the most likely reason to stop.

Switching between them

Usually possible after a clinical review, and the two real risks are a supply gap while a new intake is processed and a new prescriber restarting titration rather than continuing your dose. Confirm dose continuity in writing before cancelling anything, because a month back at 2.5 mg is a month of lost progress no price difference recovers.

If you are already on one of them

Moving from SkinnyRx to Yucca Health is worth $492 over a year. Set that against two real switching costs: a gap in supply while a new intake is reviewed, and the possibility that a new prescriber restarts titration rather than continuing your dose. Ask about dose continuation in writing before cancelling anything, because a month back at 2.5 mg is a month of lost progress no price difference recovers.

Fee structure, side by side

SkinnyRx charges no recurring fee on top of medication. Yucca Health charges no recurring fee.

This is where most published comparisons break. A table quoting medication alone understates a membership programme by the full fee, every month, for as long as you stay. Every figure here folds it in, which is why our number can be higher than the one on a programme's own homepage.

Care model and what it buys

SkinnyRx: async, labs not required, none published. Yucca Health: async, labs not required, none published.

Video visits, included laboratory work and real clinician access cost money to provide, and programmes providing them are rarely cheapest. That is what you are paying for. The failure is paying a premium for an asynchronous questionnaire a cheaper programme provides identically.

Verification, which outranks both

SkinnyRx: not named. Yucca Health: named physicians.

A programme that will not name the pharmacy compounding your medicine is asking you to inject an unidentified preparation weekly. State boards publish licensee registers and FDA publishes outsourcing-facility registrations and warning letters, all free and searchable — but only if you have a name. That question outranks a price difference of almost any size.

Which is cheaper depends on where you land

A single annual comparison assumes one maintenance dose. This runs both programmes at every plausible outcome, over one year and three.

First-year and three-year divergence by maintenance dose. Captured 2026-08-05.
If you maintain atSkinnyRx yr 1Yucca Health yr 1Gap yr 1CheaperGap over 3 yrs
5 mg$3,588$3,096$492Yucca Health$1,476
7.5 mg$3,588$3,096$492Yucca Health$1,476
10 mg$3,588$3,096$492Yucca Health$1,476
12.5 mg$3,588$3,096$492Yucca Health$1,476
15 mg$3,588$3,096$492Yucca Health$1,476

Read the final column before the first. A gap that looks modest over twelve months compounds into the three-year figure, and the withdrawal evidence for this drug class means three years is the more honest planning horizon.

What each one is actually charging for

SkinnyRx: $299 medication, no recurring fee. Yucca Health: $258 medication, no recurring fee.

Both use the same fee structure, so the medication figures are directly comparable — which is unusual enough in this market to be worth stating.

What committing to a term does to the answer

SkinnyRx publishes no prepaid rate.

Yucca Health publishes $225 a month on its 6-month plan, saving $396 a year.

Prepaying converts a monthly decision into one that is effectively final, because compounded medication is generally not refundable once shipped. During titration that is the wrong structure: you would be committing against the most likely reason to stop. After a stable cycle at maintenance it is reasonable, and it can change which of these two is cheaper.

What $492 a year actually buys

The gap between these two over a first year is $492, about 14% of the larger figure. Expressed differently, it is roughly 1.9 months of therapy at Yucca Health's maintenance rate, or $1,476 across the three-year horizon the withdrawal evidence implies.

Whether that is decisive depends on what SkinnyRx provides that Yucca Health does not. On the published record: SkinnyRx offers async against async at Yucca Health.

If the answer is nothing you will use, the gap is simply a gap. If it includes clinician access during titration, when dose questions arrive weekly, it may be the better purchase — but that is a judgement about your first three months rather than about the annual total.

How the pricing models interact

Both hold one price at every strength, so the ranking here does not move with your dose. That is unusual: most pairings in this market mix a flat programme with a dose-scaled one, and the answer flips somewhere on the ladder.

It also means the comparison is unusually clean. Whatever your prescriber decides, Yucca Health stays $41 a month cheaper at every tier. Decide on disclosure, care model and terms, because price has already been settled.

Committing to a term changes the answer, and the risk

SkinnyRx publishes no prepaid rate; Yucca Health publishes $225 on a 6-month plan.

Prepaying lowers the rate and makes the money effectively unrecoverable, because compounded medication is generally not refundable once shipped. Entering a term during titration commits cash against the single most likely reason to stop, which is not tolerating the drug.

The sequencing that protects you is monthly billing until you have held a maintenance dose for a full cycle, then a term once the main reason to stop has passed. Two questions before committing, both answerable in writing: does the discounted rate hold for the whole term or revert at renewal, and what happens if a clinician stops your prescription mid-term.

Both figures carry the same evidence grade

Both are recorded as source verified, so the comparison is at least like for like. That is not the same as both being right: a shared evidence grade means we applied the same standard, not that the underlying numbers have been independently confirmed twice.

Check both against the providers' own pages before acting. Each programme page here links directly to the source we captured, with a Wayback lookup beside it.

Moving from SkinnyRx to Yucca Health, and what it costs

The arithmetic is $492 over a year. The two costs that eat it are a supply gap while a new intake is reviewed, and a new prescriber restarting titration rather than continuing your dose.

The second is the expensive one. A month back at the starter dose is a month reproducing progress you had already made, and on Yucca Health's pricing that month costs $258 while delivering a quarter of the drug. Ask for dose continuation in writing before cancelling anything, and do not cancel until the new programme has shipped.

Take three things with you: your current dose and the date you reached it, the concentration printed on your current vial, and any record of adverse effects with dates. Vial concentrations are not standardised between compounders, and carrying instructions from an old vial to a new one is a real hazard rather than a theoretical one.

What neither table can tell you

Whether shipments arrive on time, how fast a clinician replies, whether a dose adjustment takes two days or two weeks, and what happens when a cold-chain shipment fails. Those decide satisfaction more than price does.

We hold no measurements of any of them that we would defend, so they appear nowhere in our tables rather than being estimated into a score. The one usable proxy is what each programme publishes before it has your money: SkinnyRx and Yucca Health can be judged on that today, and the disclosure rows above are the comparison.

Re-run this at your actual maintenance dose annually. Programmes do not notify existing patients when a competitor drops below them, and several tracked programmes moved pricing more than once in the past year.

If your titration runs slower than the textbook

Roughly a third of patients hold at a dose longer than four weeks because of tolerability. Add one extra month at 5 mg and SkinnyRx costs $299 more that year against $258 at Yucca Health — a change of $41 in the gap.

On flat-rate pricing an extra month costs the maintenance rate regardless of the dose delivered, which is the one scenario where flat pricing works against you. On dose-scaled pricing it costs less but reproduces a step you had already paid for.

Neither is a reason to choose differently on its own. It is a reason to run both at one step slower than you expect and take the higher figure into the decision.

The three-year exposure

At a maintenance dose the annual difference is $492; over three years it is $1,476. At the ceiling those figures become $492 and $1,476.

Three years is the honest horizon rather than a rhetorical one. The withdrawal evidence for this class shows substantial regain after stopping, so the realistic question is not what a year costs but whether you can sustain the programme indefinitely.

A programme you abandon for cost in month fourteen has cost you more than the dearer one you would have kept, because the interruption undoes the result the spending bought.

The decision from SkinnyRx's side

You would choose SkinnyRx if its structure matches your expected course: flat pricing suits an uncertain or escalating titration, no recurring platform fee keeps the advertised figure honest, and its entry price of $299 sets your first month.

You would not choose it if the opposite is true of your course, or if the disclosure rows above leave a question you cannot get answered in writing.

The decision from Yucca Health's side

You would choose Yucca Health if its flat rate protects you against a dose increase you cannot predict, and if a single all-in figure is what you want. Its first month costs $258 and its maintenance rate is $258.

You would not choose it if the gap of $492 over a first year is decisive for your budget and nothing in its disclosure justifies the difference.

Where skinnyrx and yucca health sits in the decision

Most people arrive at this market with one question — what is cheapest — and leave with a worse one, because cheapest depends on a dose nobody has chosen yet and a fee structure that is not in the advertisement.

6 of the 17 priced programmes charge a mandatory recurring fee on top of medication. 11 hold one price at every strength; the rest reprice as you climb. Those two facts reorder any ranking built on headline figures, and neither is visible without reading the terms.

The four disclosures worth insisting on

Price at the dose you will hold. The identity of the dispensing pharmacy. Whether the quoted rate survives renewal. And what is refundable before shipment.

Only 3 of 17 priced programmes publish the second, which is the one that lets you check a public state board register before injecting anything weekly. It costs a programme nothing to publish and its absence is the most reliable signal in this market.

Turning this into an email

Everything above converts into questions a programme can answer in two minutes. Anything that cannot is context rather than a check, and context does not protect you.

Send them before paying. Almost every dispute that appears in public complaint records for this category traces to a number that was never put in writing, and the programmes that reply promptly and specifically are rarely the ones patients later write about.

Where the money actually separates

A single annual figure hides when the gap opens. Tracked month by month through a first year you can see whether the difference is front-loaded during titration or accumulates quietly at maintenance.

Cumulative spend on the standard escalation: four weeks at 2.5 mg, four at 5 mg, then 10 mg. Membership included.
By end ofSkinnyRxYucca HealthGap
Month 1$299$258$41
Month 2$598$516$82
Month 3$897$774$123
Month 6$1,794$1,548$246
Month 9$2,691$2,322$369
Month 12$3,588$3,096$492

Across the year the gap reaches $492, roughly 14% of the larger total and about 1.9 months of therapy at Yucca Health's maintenance rate. Over three years at a stable dose the same difference compounds to roughly $1,476.

Does the answer change with your dose?

Yucca Health is cheaper at every strength, so this comparison does not turn on where you settle. The decision moves to what else differs: disclosure, care model, commitment terms and behaviour when a shipment fails.

Commitment and what each puts at risk

SkinnyRx publishes no prepaid term. Yucca Health publishes a prepaid rate of $225 a month on its 6-month plan.

Prepaying lowers the rate and makes the money effectively unrecoverable, because compounded medication is generally not refundable once shipped. During titration that is the wrong structure: it commits against the most likely reason to stop. After a stable cycle at maintenance it is reasonable.

Care model and what you can verify

SkinnyRx: async, labs not required, pharmacy not named, cancellation no membership on compounded.

Yucca Health: async, labs not required, pharmacy named physicians, cancellation 6-month term.

Where one names a pharmacy and the other does not, that difference outranks a modest price gap. It is the only disclosure that lets you check a public register before injecting something weekly, and it costs a programme nothing to publish.

If you are already on one of them

Moving from SkinnyRx to Yucca Health is worth $492 over a year, about 1.9 months of therapy at the cheaper rate. Set that against two real switching costs: a supply gap while an intake is reviewed, and the possibility that a new prescriber restarts titration.

Ask about dose continuation in writing before cancelling anything. A month back at 2.5 mg is a month of lost progress that no price difference recovers, and it is the most common regret reported by people who switched for a small saving.

What neither table can tell you

Shipping reliability, how fast a clinician actually replies, whether a dose adjustment takes two days or two weeks, and what happens when a cold-chain shipment fails. Those decide satisfaction more than price does, and we hold no measurements of them we would defend, so they are absent rather than estimated.

The one usable proxy is what each programme publishes before it has your money. A programme that states its price at every dose, names its pharmacy and puts cancellation terms in writing has already told you something about how it behaves when there is a problem.

Running this comparison again later

Both figures carry a capture date and both will change. Programmes do not notify existing patients when a competitor drops below them, and several tracked programmes moved pricing more than once in the past year.

Re-run this at your actual maintenance dose annually, and treat any figure older than a month as needing a re-check before you act on it.

Where both of these sit in the wider market

SkinnyRx at $3,588 and Yucca Health at $3,096 for a first year sit against a market running from $2,580 to $6,576. Both are at the cheaper end of what we track.

If neither is close to the cheapest tracked route, the useful question is not which of these two wins but why you are choosing between these two at all. The comparison matrix will show what else is available at your dose in about ten seconds.

If you are already on one of them

Moving from SkinnyRx to Yucca Health is worth $492 over a year. Set that against two real switching costs: a gap in supply while a new intake is reviewed, and the possibility that a new prescriber restarts titration rather than continuing your dose. Ask about dose continuation in writing before cancelling anything, because a month back at 2.5 mg is a month of lost progress no price difference recovers.

Fee structure, side by side

SkinnyRx charges no recurring fee on top of medication. Yucca Health charges no recurring fee.

This is where most published comparisons break. A table quoting medication alone understates a membership programme by the full fee, every month, for as long as you stay. Every figure here folds it in, which is why our number can be higher than the one on a programme's own homepage.

Care model and what it buys

SkinnyRx: async, labs not required, none published. Yucca Health: async, labs not required, none published.

Video visits, included laboratory work and real clinician access cost money to provide, and programmes providing them are rarely cheapest. That is what you are paying for. The failure is paying a premium for an asynchronous questionnaire a cheaper programme provides identically.

Verification, which outranks both

SkinnyRx: not named. Yucca Health: named physicians.

A programme that will not name the pharmacy compounding your medicine is asking you to inject an unidentified preparation weekly. State boards publish licensee registers and FDA publishes outsourcing-facility registrations and warning letters, all free and searchable — but only if you have a name. That question outranks a price difference of almost any size.

Which is cheaper depends on where you land

A single annual comparison assumes one maintenance dose. This runs both programmes at every plausible outcome, over one year and three.

First-year and three-year divergence by maintenance dose. Captured 2026-08-05.
If you maintain atSkinnyRx yr 1Yucca Health yr 1Gap yr 1CheaperGap over 3 yrs
5 mg$3,588$3,096$492Yucca Health$1,476
7.5 mg$3,588$3,096$492Yucca Health$1,476
10 mg$3,588$3,096$492Yucca Health$1,476
12.5 mg$3,588$3,096$492Yucca Health$1,476
15 mg$3,588$3,096$492Yucca Health$1,476

Read the final column before the first. A gap that looks modest over twelve months compounds into the three-year figure, and the withdrawal evidence for this drug class means three years is the more honest planning horizon.

What each one is actually charging for

SkinnyRx: $299 medication, no recurring fee. Yucca Health: $258 medication, no recurring fee.

Both use the same fee structure, so the medication figures are directly comparable — which is unusual enough in this market to be worth stating.

What committing to a term does to the answer

SkinnyRx publishes no prepaid rate.

Yucca Health publishes $225 a month on its 6-month plan, saving $396 a year.

Prepaying converts a monthly decision into one that is effectively final, because compounded medication is generally not refundable once shipped. During titration that is the wrong structure: you would be committing against the most likely reason to stop. After a stable cycle at maintenance it is reasonable, and it can change which of these two is cheaper.

What $492 a year actually buys

The gap between these two over a first year is $492, about 14% of the larger figure. Expressed differently, it is roughly 1.9 months of therapy at Yucca Health's maintenance rate, or $1,476 across the three-year horizon the withdrawal evidence implies.

Whether that is decisive depends on what SkinnyRx provides that Yucca Health does not. On the published record: SkinnyRx offers async against async at Yucca Health.

If the answer is nothing you will use, the gap is simply a gap. If it includes clinician access during titration, when dose questions arrive weekly, it may be the better purchase — but that is a judgement about your first three months rather than about the annual total.

How the pricing models interact

Both hold one price at every strength, so the ranking here does not move with your dose. That is unusual: most pairings in this market mix a flat programme with a dose-scaled one, and the answer flips somewhere on the ladder.

It also means the comparison is unusually clean. Whatever your prescriber decides, Yucca Health stays $41 a month cheaper at every tier. Decide on disclosure, care model and terms, because price has already been settled.

Committing to a term changes the answer, and the risk

SkinnyRx publishes no prepaid rate; Yucca Health publishes $225 on a 6-month plan.

Prepaying lowers the rate and makes the money effectively unrecoverable, because compounded medication is generally not refundable once shipped. Entering a term during titration commits cash against the single most likely reason to stop, which is not tolerating the drug.

The sequencing that protects you is monthly billing until you have held a maintenance dose for a full cycle, then a term once the main reason to stop has passed. Two questions before committing, both answerable in writing: does the discounted rate hold for the whole term or revert at renewal, and what happens if a clinician stops your prescription mid-term.

Both figures carry the same evidence grade

Both are recorded as source verified, so the comparison is at least like for like. That is not the same as both being right: a shared evidence grade means we applied the same standard, not that the underlying numbers have been independently confirmed twice.

Check both against the providers' own pages before acting. Each programme page here links directly to the source we captured, with a Wayback lookup beside it.

Moving from SkinnyRx to Yucca Health, and what it costs

The arithmetic is $492 over a year. The two costs that eat it are a supply gap while a new intake is reviewed, and a new prescriber restarting titration rather than continuing your dose.

The second is the expensive one. A month back at the starter dose is a month reproducing progress you had already made, and on Yucca Health's pricing that month costs $258 while delivering a quarter of the drug. Ask for dose continuation in writing before cancelling anything, and do not cancel until the new programme has shipped.

Take three things with you: your current dose and the date you reached it, the concentration printed on your current vial, and any record of adverse effects with dates. Vial concentrations are not standardised between compounders, and carrying instructions from an old vial to a new one is a real hazard rather than a theoretical one.

What neither table can tell you

Whether shipments arrive on time, how fast a clinician replies, whether a dose adjustment takes two days or two weeks, and what happens when a cold-chain shipment fails. Those decide satisfaction more than price does.

We hold no measurements of any of them that we would defend, so they appear nowhere in our tables rather than being estimated into a score. The one usable proxy is what each programme publishes before it has your money: SkinnyRx and Yucca Health can be judged on that today, and the disclosure rows above are the comparison.

Re-run this at your actual maintenance dose annually. Programmes do not notify existing patients when a competitor drops below them, and several tracked programmes moved pricing more than once in the past year.

If your titration runs slower than the textbook

Roughly a third of patients hold at a dose longer than four weeks because of tolerability. Add one extra month at 5 mg and SkinnyRx costs $299 more that year against $258 at Yucca Health — a change of $41 in the gap.

On flat-rate pricing an extra month costs the maintenance rate regardless of the dose delivered, which is the one scenario where flat pricing works against you. On dose-scaled pricing it costs less but reproduces a step you had already paid for.

Neither is a reason to choose differently on its own. It is a reason to run both at one step slower than you expect and take the higher figure into the decision.

The three-year exposure

At a maintenance dose the annual difference is $492; over three years it is $1,476. At the ceiling those figures become $492 and $1,476.

Three years is the honest horizon rather than a rhetorical one. The withdrawal evidence for this class shows substantial regain after stopping, so the realistic question is not what a year costs but whether you can sustain the programme indefinitely.

A programme you abandon for cost in month fourteen has cost you more than the dearer one you would have kept, because the interruption undoes the result the spending bought.

The decision from SkinnyRx's side

You would choose SkinnyRx if its structure matches your expected course: flat pricing suits an uncertain or escalating titration, no recurring platform fee keeps the advertised figure honest, and its entry price of $299 sets your first month.

You would not choose it if the opposite is true of your course, or if the disclosure rows above leave a question you cannot get answered in writing.

The decision from Yucca Health's side

You would choose Yucca Health if its flat rate protects you against a dose increase you cannot predict, and if a single all-in figure is what you want. Its first month costs $258 and its maintenance rate is $258.

You would not choose it if the gap of $492 over a first year is decisive for your budget and nothing in its disclosure justifies the difference.

Where skinnyrx and yucca health sits in the decision

Most people arrive at this market with one question — what is cheapest — and leave with a worse one, because cheapest depends on a dose nobody has chosen yet and a fee structure that is not in the advertisement.

6 of the 17 priced programmes charge a mandatory recurring fee on top of medication. 11 hold one price at every strength; the rest reprice as you climb. Those two facts reorder any ranking built on headline figures, and neither is visible without reading the terms.

The four disclosures worth insisting on

Price at the dose you will hold. The identity of the dispensing pharmacy. Whether the quoted rate survives renewal. And what is refundable before shipment.

Only 3 of 17 priced programmes publish the second, which is the one that lets you check a public state board register before injecting anything weekly. It costs a programme nothing to publish and its absence is the most reliable signal in this market.

Turning this into an email

Everything above converts into questions a programme can answer in two minutes. Anything that cannot is context rather than a check, and context does not protect you.

Send them before paying. Almost every dispute that appears in public complaint records for this category traces to a number that was never put in writing, and the programmes that reply promptly and specifically are rarely the ones patients later write about.

Primary sources

Open these rather than taking our word for it. Every one is a regulator, a trial registry, a label, an accreditor or the manufacturer.

  1. FDA — Human Drug Compounding
  2. NABP — State Boards of Pharmacy directory
  3. SURMOUNT-1 (NCT04184622)
  4. FDA — Compounding and the FDA: Questions and Answers

Next step

Compare every programme on one screen

The matrix carries all-in price at every dose, fee structure, commitment terms, pharmacy disclosure and verification status for every programme we track.

Open the comparison matrix How all-in cost is calculated

Common questions

Is SkinnyRx or Yucca Health cheaper?

Yucca Health is cheaper, at about $3,096 for a first year against $3,588 — a difference of $492.

Do SkinnyRx and Yucca Health charge a membership on top of medication?

SkinnyRx: no. Yucca Health: no. Every figure on this page includes it where charged.

Does SkinnyRx or Yucca Health name its dispensing pharmacy?

SkinnyRx: not named. Yucca Health: named physicians. It is the disclosure that lets you check a state board register before you inject anything weekly.

Can I switch between them mid-treatment?

Usually yes, after a clinical review. Confirm dose continuity in writing and do not cancel the old programme until the new one has shipped, because a supply gap costs more than a price difference.

Is either SkinnyRx or Yucca Health FDA-approved?

Compounded preparations are not FDA-approved and are not reviewed by FDA for safety, effectiveness or quality before marketing. Where a programme supplies brand product, that product is approved; the programme around it is not a regulated entity in the same sense.